Unleash Your Extra Strength

With Avmacol® Extra Strength, a little support goes an extra long way.

What is Avmacol® Extra Strength?

Avmacol® Extra Strength is a patented, sulforaphane-producing supplement that works in combination with Maitake mushroom extract (containing beta-glucans) to support your body's natural detoxification process better than sulforaphane alone.* Avmacol® Extra Strength provides glucoraphanin, also known as sulforaphane glucosinolate, and active myrosinase enzyme, which are the essential ingredients needed for sulforaphane production. Without active myrosinase enzyme, one may not be able to reap sulforaphane’s many health-promoting benefits.

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Sulforaphane Producing Supplement Avmacol Extra Strength 75 count bottle

What are the Ingredients?

Avmacol® Extra Strength contains the essential ingredients necessary for sulforaphane production in the body, broccoli seed extract (Glucoraphanin) and Myrosimax® (Active Myrosinase Enzyme). Avmacol® Extra Strength also contains Maitake mushroom extract for added immune and detoxification support.

Supplement Facts

Directions for Use:
Take 1 tablet per day or as directed by a physician. If you have any condition that requires medical attention always consult your physician before taking any dietary supplement.

Keep in a cool, dry place.

Important: Tamper evident seal under cap. Do not use if seal is broken or missing.

OTHER INGREDIENTS: MICROCRYSTALLINE CELLULOSE AND MALTODEXTRIN

CONTAINS LESS THAN 2% OF: SILICON DIOXIDE, MODIFIED CELLULOSE GUM AND MAGNESIUM STEARATE

Serving Size 1 Tablet
Servings Per Container 30

Amount Per Serving

% Daily Value

Total Carbohydrates

less than 1 g

Vitamin C from Asorbic Acid

25 mg

28%

Proprietary Sulforaphane Glucosinolate (Glucoraphanin) & Myrosinase Blend

25 mg

28%

How Maitake Mushroom Extract Works in Combination with Sulforaphane

The Maitake mushroom extract (containing beta-glucans) works in combination with sulforaphane to support your body’s natural detoxification process better than sulforaphane alone.* In addition, the Maitake mushroom extract found in Avmacol® Extra Strength provides the added bonus of immune support by promoting neutrophil function and natural killer cell activity.

natural killer cells with broccoli floret and maitake mushroom

Learn more about Sulforaphane 

The Science Behind Avmacol®
Extra Strength

The combination of sulforaphane and Maitake extract supports the movement (or translocation) from the cytoplasm to the nucleus of NRF2 and increases the levels of certain Phase 2 enzymes. Below are images of a technique called immunofluorescence which illustrate how much protein is being produced in the cell and the location of that protein.

Translocation of NRF2 into the Nucleus Following Exposure to Sulforaphane and Maitake Mushroom Extract

Translocation of NRF2 into the Nucleus without Exposure to Sulforaphane and Maitake Mushroom Extract

control

Translocation of NRF2 into the Nucleus Following Exposure to Sulforaphane and Maitake Mushroom Extract

sulforaphane + maitake

In control cells (left panel), the green staining indicates that NRF2 remains largely in the cytoplasm (arrows) without much protein located in the nucleus, which is counter-stained in blue. When cells are exposed to sulforaphane and Maitake (right panel), NRF2 moves to the nucleus (arrows) where it can bind to DNA to turn on expression of certain Phase 2 enzymes.

Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1

NQO1 Protein Expression in THLE2 Liver Cells

control

NQO1 Protein Expression in THLE2 Liver Cells after taking sulforaphane-producing supplement and maitake mushroom extract

sulforaphane + maitake

In control cells (left panel) NQO1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of NQO1 staining, representing the amount of protein, is increased.

HO-1 Protein Expression in THLE2 Liver Cells

control

HO-1 Protein Expression in THLE2 Liver Cells after taking a sulforaphone & maitake supplement

sulforaphane + maitake

In control cells (left panel) HO-1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of HO-1 staining, representing the amount of protein, is increased.

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Who Would Benefit from Avmacol® Extra Strength?

We are capable of incredible things; and when our bodies get the support they need, the results can be amazing. Avmacol^® unleashes the power of broccoli to help your body fight off toxin-related stress at the cellular level.

Learn more about our Avmacol® Community 

Unleash Your Extra Strength

What is Avmacol® Extra Strength?

What are the Ingredients?

Supplement Facts

How Maitake Mushroom Extract Works in Combination with Sulforaphane

The Science Behind Avmacol® Extra Strength

Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1

Who Would Benefit from Avmacol® Extra Strength?

The Science Behind Avmacol®
Extra Strength